Abstract
After publishing a genome scan and follow-up fine mapping, suggesting schizophrenia
and bipolar disorder linkage to chromosome 3q29, we now genotyped 11 additional SNPs (single
nucleotide polymorphisms), in order to narrow down a potential candidate region. Linkage was
performed using the GENEHUNTER program version 2.1r3. A NPL score Zall of 3.891 (p=0.000156)
was observed with SNP rs225. In short, we found significant linkage scores most telomeric on
chromosome 3q29, spanning 3.46 Mbp (7 SNPs).
and bipolar disorder linkage to chromosome 3q29, we now genotyped 11 additional SNPs (single
nucleotide polymorphisms), in order to narrow down a potential candidate region. Linkage was
performed using the GENEHUNTER program version 2.1r3. A NPL score Zall of 3.891 (p=0.000156)
was observed with SNP rs225. In short, we found significant linkage scores most telomeric on
chromosome 3q29, spanning 3.46 Mbp (7 SNPs).
Originalsprache | Englisch |
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Seiten (von - bis) | 501 - 505 |
Fachzeitschrift | European Neuropsychopharmacology |
Jahrgang | 17 |
Ausgabenummer | 6-7 |
Publikationsstatus | Veröffentlicht - 1 Nov. 2007 |