Measuring High-Risk Patients’ Preferences for Pharmacogenetic Testing to Reduce Severe Adverse Drug Reaction: A Discrete Choice Experiment

Di Dong, Semra Ozdemir, Yong Mong Bee, Sue-Anne Toh, Marcel Bilger, Eric Finkelstein

Publication: Scientific journalJournal articlepeer-review



To investigate patient preferences and willingness to pay (WTP) for a genetic test that can reduce the risk of life-threatening adverse drug reactions (ADRs). We hypothesize that test features (risk of developing the adverse reaction with and without testing, test cost, and treatment cost) and the choice context (physician recommendation and the most common choice made by peer patients) will influence choices.

A discrete choice experiment was conducted in which 189 patients at high risk for gout were asked to choose between treatment options that varied along key attributes. A latent class logit model was used to analyze the choice data and test the hypotheses.
Original languageEnglish
Pages (from-to)767 - 775
JournalValue in Health
Issue number6
Publication statusPublished - 2016

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